Review Articles Hemorrhage Sepsis Microvascular Dysfunction Proof of Concept Other References
Please see Bibliography of References for a list of abstracts, manuscripts and posters.
Review Articles

Monitoring trauma and intensive care unit resuscitation with tissue hemoglobin oxygen saturation
Santora RJ, Moore FA. Crit Care. 2009;13(Suppl 5):S10. [Abstract]

Probing the limits of regional tissue oxygenation measures
Pinsky M, Payen D. Crit Care. 2009;13(Suppl 5):S1. [Abstract]

Role of storage time of red blood cells on microcirculation and tissue oxygenation in critically ill patients
Frenzel T, Westphal-Varghese B, Westphal M. Curr Opin Anaesth. 2009;22(2):275-280. [Abstract]

Muscle StO2 in critically ill patients
Creteur J. Curr Opin Crit Care. 2008;14(3):361-366. [Abstract]

NIRS determination of tissue oxygenation in sepsis
Creteur J, Vincent JL. Intl J Int Care. 2008;Summer:19-22. [Abstract]

Is muscle StO2 an appropriate variable for investigating early compensatory tissue mechanisms under physiological and pathological conditions?
De Blasi RA. Int Care Med. 2008;34(9):1557-1559. [Abstract]

Computerized clinical decision support for the traumatic shock resuscitation
Santora RJ, McKinley BA, Moore FA. Curr Opin Crit Care. 2008;14(6):679-684. [Abstract]

Measurement of skeletal muscle tissue oxygenation in the critically ill
Strahovnik I, Podbregar M. Signa Vitae. 2008;3(1):43-50. [Abstract]

Monitoring and improving microcirculatory dysfunction
Scheeren T. Euroanaesthesia 2008; May 31-June 3, 2008; Copenhagen, Denmark. [Abstract]

Near-infrared spectroscopy: potential clinical benefits in surgery
Cohn SM. J Am Coll Surg. 2007;205(2):322–332. [Abstract]

Searching for non-invasive markers of tissue hypoxia
Puyana JC, Pinsky MR. Crit Care. 2007;11(1):116. [Abstract]

Near-infrared spectroscopy in resuscitation
Cohn SM, Crookes BA, Proctor KG. J Trauma. 2003;54(5, Suppl):S199-S202. [Abstract]





The InSpectra™ StO2 Tissue Oxygenation Monitor provides a noninvasive, continuous, real-time, and direct measurement of hemoglobin oxygen saturation in tissue (StO2), providing trauma teams the ability to measure tissue oxygen saturation and monitor it during resuscitation. It is the only perfusion status monitor designed for trauma environments. The InSpectra StO2 Tissue Oxygenation Monitor uses near infrared light to illuminate tissue, and then analyzes the returned light to produce a quantitative measurement of oxygen saturation in the tissue's microcirculation.

The StO2 Trauma Study researched the role that tissue oxygen saturation monitoring could play in hemorrhagic shock and resuscitation. Study results demonstrate that StO2 measurements less than 75% may indicate serious hypoperfusion in trauma patients and that StO2 functions as well as base deficit in indicating hypoperfusion in trauma patients.