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Compartment Syndrome

The InSpectra™ StO2 Tissue Oxygenation Monitor has not been cleared by the FDA for use in diagnosing compartment syndrome. Additional clinical studies are required to establish the value of these measurements in assessing patient status relating to compartment syndrome. Click here to see the complete Indications for Use.

Monitoring For Compartmental Syndrome Using Near-Infrared Spectroscopy: A Non-Invasive, Continuous, Transcutaneous Monitoring Technique
Garr JL, Gentilello LM, Cole PA, Mock CN, Matsen FA.
J Trauma. 1999; 46:613-618

In acute compartment syndrome of the upper and lower extremity, increased tissue pressure severely compromises blood flow through skeletal muscle, resulting in muscle ischemia. In porcine models of compartment syndrome, StO2 was shown to correlate strongly with tissue pressure measurements and loss of neuromuscular function.

Near-Infrared Spectroscopy: A Potential Method For Continuous, Transcutaneous Monitoring For Compartmental Syndrome In Critically Injured Patients.
Arbabi S, Brundage SI, Gentilello LM
J Trauma. 1999; 47:829-833

In another porcine model of compartment syndrome, hypotension was added to hypoxemia and demonstrated that the InSpectra™ System could measure compromised tissue oxygenation in the presence of unstable, shock-like physiology.

Utility Of Near-Infrared Spectroscopy In The Diagnosis Of Lower Extremity Compartment Syndrome.
Giannotti G, Cohn SM, Brown M, Varela JE, McKenney MG, Wiseberg JA
J Trauma. 2000;48: 396-401

In patients diagnosed with lower extremity compartment syndrome, Giannotti et al identified a statistically significant difference in StO2 measurements between affected and control limbs.

The InSpectra™ StO2 Tissue Oxygenation Monitor provides a direct, absolute measurement of hemoglobin oxygen saturation in tissue (StO2), providing trauma teams the ability to measure tissue oxygenation and monitor it during resuscitation. It is the only tissue oxygenation monitor designed for trauma environments. The InSpectra StO2 Tissue Oxygenation Monitor uses near infrared light to illuminate tissue, and then analyzes the returned light to produce a quantitative measurement of oxygen saturation in the tissue's microcirculation.

The StO2 Trauma Study researched the role that tissue oxygen saturation monitoring could play in hemorrhagic shock and resuscitation. Study results demonstrate that StO2 measurements less than 75% may indicate serious hypoperfusion in trauma patients and that StO2 functions as well as base deficit in indicating hypoperfusion in trauma patients.