Hemorrhagic Shock
Click here to see the complete Indications for Use for the
InSpectra™ StO2 Tissue Oxygenation Monitor.
Cohn SM, Nathens AB, Moore FA, Rhee P, Puyana JC, Moore EE, Beilman GJ.
Presented at the American Association for the Surgery of Trauma Annual Meeting, September 2006.
A prospective observational clinical study was conducted over a 15-month period to identify the role that tissue oxygen saturation (StO2) monitoring with the InSpectra™ StO2 System could play in hemorrhagic shock and resuscitation. The study was designed to determine if StO2 measurements on the thenar eminence are an indicator of hypoperfusion. Multiple organ dysfunction syndrome (MODS) was chosen as an indicator of hypoperfusion because it is generally accepted that early hypoperfusion is associated with later development of organ dysfunction. The study also assessed StO2’s ability to monitor tissue oxygenation changes during resuscitation. Seven Level 1 trauma centers enrolled a total of 383 severely injured patients.
Click here for a summary of study results.
Can Muscle Near Infrared Spectroscopy (NIR) Identify the Severity of Shock in Trauma Patients? Bruce Crookes, MD, Stephen Cohn, MD, FACS*, Scott Bloch, BS, Matthew Proctor, Ron Manning, RN Pam Li, RN, Jose Amortegui, MD, Lorne Blackbourne, MD, Carl Schulman, MD, Fahim Habib, MD, Dror Soffer, Robert Benjamin, MD. University of Miami.
Presented at: Eastern Association for the Surgery of Trauma Annual Meeting, January 2004 Near Infrared Spectroscopy (NIR) using the
InSpectra™ System can be utilized to continuously and non-invasively determine tissue oxygen saturation (StO
2) in muscle and represents a potential method of non-invasively assessing the severity of shock.
Tissue Hemoglobin O2 Saturation During Resuscitation of Traumatic Shock Monitored Using Near Infrared SpectrometryMcKinley BA, Marvin RG, Cocanour CS, Moore FA
J Trauma. 2000;48:637-642
HTI's NIR spectrometer measurement of StO
2 in the deltoid muscle correlates to DO
2I (r = 0.95) in severely injured trauma patients.
Near-Infrared Spectroscopy in ResuscitationCohn S, Crookes BA, Proctor KG
J Trauma. 2003;Vol 54 No 5:S199-S202
A review of published literature related to hemorrhagic shock by Dr. Stephen Cohn et al on near-infrared (NIR) technology indicates that NIR devices developed to measure skeletal muscle tissue are capable of measuring local vs. systemic hypoxia, providing the potential for clinical utility in hemorrhagic shock resuscitation.
Use of Near-Infrared Spectroscopy in Early Determination of Irreversible Hemorrhagic ShockGreg J. Beilman, MD, Jodie H. Taylor, MD, University of Minnesota. Dean Myers, BS, Kristine Mulier, MS
Presented at: American Association for the Surgery of Trauma Annual Meeting, September 2004 Progression to irreversible shock may not be clinically apparent until a patient has depleted stores of fluid and blood. Non-invasive monitoring of leg and stomach StO
2 with the
InSpectra™ System identified unresuscitatable animals after the initial resuscitative bolus.
Near-Infrared Spectroscopy Measurement Of Regional Tissue Oxyhemoglobin Saturation During Hemorrhagic ShockBeilman GJ, Groehler KE, Lazaron V, Ortner JP
Shock. 1999;12:196-200
In a splenectomized porcine model of hemorrhagic shock, hind leg measurements of StO
2 taken with Hutchinson Technology's tissue spectrometer, and oxygen delivery measurements taken from pulmonary arterial catheterization, show a linear relationship with high degree of correlation (0.94).