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Basic Knowledge
Introduction to StO2 in Clinical Applications
Tom Ahrens, DNS RN CCNS FAAN
Objectives:
  • Describe common clinical scenarios where traditional vital signs may be inadequate in detecting shock and tissue hypoperfusion
  • Describe the normal range of StO2 and how to interpret high & low StO2 values
  • Describe the value of StO2 monitoring during the administration of IV fluids, inotropes and vasopressors. 
 

Part 1: Jan's Streetwise StO2 Physiology
Jan Bakker, MD, PhD
Objectives:
  • Provide an introduction to the basic physiologic priciples of StO2
  • Describe StO2's relationship to other clinical parameters in the assessment of critically-ill patients
  • Describe the basics of oxygen demand, supply and extraction
  • Describe the relationship of StO2 to changes in blood flow, PEEP and cardiac output
  • Describe the relationship of StO2 (tissue) to ScVO2 (central venous) and SvO2 (mixed venous) oxygen saturation

Play Video File

 
Part 2: Jan says: "Low StO2 MUST be Investigated!"
Jan Bakker, MD, PhD
Objectives:
  • Provide an introduction to clinical situations with StO2 and other clinical paramenters
  • Review the evidence describing StO2 and tissue perfusion monitoring in critically-ill patients
  • Describe the basics of oxygen demand, supply and extraction
  • Describe the relationship of StO2 to lactate and other current markers of tissue oxygenation
  • Understand StO2's relationship with vasopressors 
 
Hemodynamic Monitoring: Macro and Microcirculation
Prof. Dr. Can Ince
Objectives:
  • Understand the difference between blood pressure and tissue perfusion
  • Understand the relationship between tissue perfusion and tissue oxygenation
  • Understand StO2 as a measure of tissue oxygenation
Play Video File

 

Location, Location, Location – SaO2, SpO2, ScvO2, SvO2, StO2
Barbara McLean MN, RN, CCRN, CCNS, CRNP, FCCM
Objectives:
  • Compare/Contrast SaO2, SpO2, ScvO2, SvO2, and StO2
  • Physiologic and clinical differences of vital signs
  • Clinical cases illustrating hemoglobin oxygen saturations
 
Are We Done Yet? Differential Assessment of tissue perfusion
Christine Schulman RN, MS, CNS, CCRN
Objectives:
  • Clinical implications of using serum lactate, base deficit, and tissue oxygen saturation
  • Challenges of chemical markers to assess resuscitation status
  • Resuscitation status and intervention planning
 
Interventions
Resuscitation and Massive Transfusion in Trauma Patients: StO2 Predicts Poor Outcome
Frederick A. Moore MD
Objectives:
  • ICU Shock Resuscitation
  • Predicting outcomes in trauma patients
  • Massive Transfusion
  • Sepsis Resuscitation
 
Clinical Relevance
StO2 in hypoperfused patients in the Emergency Department
Eric Maniago, MD, FACEP
Objectives:
  • Incorporating StO2 into guidelines to identify and monitor hypoperfused patients
  • Using StO2 to identify and monitor patients with occult bleeding

 
Identifying hypoperfusion in hypothermic trauma patients
Greg Beilman MD
Objectives:
  • Hypothermia’s relationship to mortality and MODS
  • Utility of InSpectra StO2 System as a measure of hypoperfusion
  • Identify hypoperfusion in a cold trauma patient
 
StO2 in the evaluation of combat casualties
Alec Beekley MD, FACS
Objectives:
  • Using StO2 to assist in identifying hypoperfusion
  • Utility of StO2 in the resuscitation of trauma patients
  • Using StO2 to predict the need for life-saving interventions and blood transfusion
 
Exploring tissue oxygen metabolism and vasoreactivity by measuring StO2 during a vascular occlusion test in patients with severe sepsis
Jacques Creteur MD, PhD
Objectives:
  • VOT and StO2 in management of critically ill patients
  • Using StO2 to assess microvascular dysfunction
  • Effects of therapeutic interventions on vasoreactivity in septic patients
 
 
Monitoring Tissue Oxygenation (StO2) in Sepsis Patients
Laura Moore MD
Objectives:
  • Pathophysiology sepsis and physiology StO2
  • Challenges in treating sepsis patients
  • Interventions (blood, vasocative meds, fluids)
  • Case studies and protocols that incorporated use of StO2
 


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The InSpectra™ StO2 Tissue Oxygenation Monitor provides a noninvasive, continuous, real-time, and direct measurement of hemoglobin oxygen saturation in tissue (StO2), providing trauma teams the ability to measure tissue oxygen saturation and monitor it during resuscitation. It is the only perfusion status monitor designed for trauma environments. The InSpectra StO2 Tissue Oxygenation Monitor uses near infrared light to illuminate tissue, and then analyzes the returned light to produce a quantitative measurement of oxygen saturation in the tissue's microcirculation.

The StO2 Trauma Study researched the role that tissue oxygen saturation monitoring could play in hemorrhagic shock and resuscitation. Study results demonstrate that StO2 measurements less than 75% may indicate serious hypoperfusion in trauma patients and that StO2 functions as well as base deficit in indicating hypoperfusion in trauma patients.